guillain-barré syndrome as first presentation of non-hodgkin's lymphoma

نویسندگان

abolhassan ertiaei department of neurosurgery, school of medicine, tehran university of medical sciences, tehran, iran.

mahsa ghajarzadeh brain and spinal injury research center, imam khomeini hospital, tehran university of medical sciences, tehran, iran.

azizollah javdan department of neurosurgery, school of medicine, tehran university of medical sciences, tehran, iran.

abbas taffakhori department of neurology, iranian center of neurological research, imam khomeini hospital, tehran university of medical sciences, tehran, iran.

چکیده

we present a woman referred with underlying non-hodgkin's lymphoma (nhl) masquerading clinically with guillain-barré syndrome (gbs) like syndrome. at first evaluation, chest ct-scan along with brain and whole spine mri were normal. electrodiagnostic studies were in favor of acute generalized polyradiculoneuropathy. laboratory evaluation revealed hypoglycorrhachia. she treated with plasmapheresis after two weeks; she was discharged from hospital, but neurological recovery was not complete. after 6 months, she came back with acute onset of weakness in lower limbs, back pain, fever and urinary incontinence. pinprick and light touch complete sensory loss was found beneath umbilicus. thoracic mri with contrast revealed a dorsal epidural mass extending smoothly from t8 to t12 (10 cm) with spinal cord compression. she underwent urgent laminectomy for spinal cord decompression. histological examination revealed small round cell tumor suggestive of malignant t-cell type lymphoma. in cases with guillain-barré syndrome presentation, systemic hematologic disorders such as non-hodgkin's lymphoma should be considered as one of the differential diagnosis of underlying disease.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Guillain-Barré Syndrome as First Presentation of Non-Hodgkin's Lymphoma.

We present a woman referred with underlying non-Hodgkin's lymphoma (NHL) masquerading clinically with Guillain-Barré syndrome (GBS) like syndrome. At first evaluation, chest CT-Scan along with brain and whole spine MRI were normal. Electrodiagnostic studies were in favor of acute generalized polyradiculoneuropathy. Laboratory evaluation revealed hypoglycorrhachia. She treated with plasmapheresi...

متن کامل

Skin rash as early presentation of Guillain-Barré syndrome.

We report an unusual case of Guillain-Barre syndrome in a 36-year old gentleman, diagnosed based on clinical presentation, CSF analysis and nerve study tests findings, who presented to our department for elective cystoscopy and discovered at the day of surgery to have macular skin rash over the trunk and upper limbs, surgery was postponed. Then and after 12 hours he started to develop the class...

متن کامل

Non-Hodgkin lymphoma and Guillain-Barré syndrome: a rare association.

Non-Hodgkin lymphoma (NHL) is a neoplastic transformation of cells that reside predominantly within lymphoid tissues, which may be of Bor T-cell origin. There is a slight male-to-female predominance and a higher incidence in whites than blacks. Incidence rises steadily with age, especially after 40 years. Extranodal lymphomas usually present as a mass, and sometimes as a fever of unknown origin...

متن کامل

Characteristics of Guillain-Barré syndrome: brief report

Background: Guillain-Barré syndrome is an autoimmune inflammatory disease, which manifests itself as an acute motor weakness of the organs, diagnosed as affecting the motor spinal nerve roots generally and causing muscle and motor weakness, the cause of this disease is the presence of active antibodies against the myelin sheath around the spinal nerve roots. Guillain-Barré syndrome is the most ...

متن کامل

bilateral ptosis as the first presentation of guillain-barre syndrome

how to cite this article: talebian a, soltani b, talebian m. bilateral ptosis as the first presentation of guillain-barre syndrome. iran j child neurol. winter 2016; 10(1):70-72. abstract objective guillain-barre syndrome (gbs) is the most common cause of acute weakness in children. it has multiple variant forms with different presentations. a rare initial sign is ptosis. in this study, we pres...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
acta medica iranica

جلد ۵۴، شماره ۷، صفحات ۴۷۱-۴۷۴

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023